Platelet Concentrate: PRP is described as a biologic product derived from autologous blood, containing a concentrated amount of platelets in the plasma fraction, typically at concentrations of more than 3 to 5 times above baseline.

Growth Factors: Platelets in PRP contain growth factors crucial for wound healing, and higher platelet concentrations have been shown to enhance this process effectively.

Tissue Repair and Regeneration: PRP, with its increased concentration of platelets and associated growth factors or cytokines, is theorized to encourage tissue repair and regeneration. This includes neocollagenesis and neoangiogenesis.

Facial Rejuvenation: PRP therapy has gained popularity for facial rejuvenation due to its effectiveness, safety, and minimal complication rates.

Mechanism of Action: PRP stimulates neocollagenesis by activating fibroblasts and removing photodamaged extracellular matrix components, leading to improved dermal elasticity and facial rejuvenation.

Preparation and Administration: PRP is prepared using a double centrifuge technique, and it can be injected into the face under local anesthetic or numbing cream to ensure patient comfort.

Treatment Plan: A recommended treatment plan involves multiple intradermal injections of PRP, often combined with micro-needling (collagen induction therapy) using a derma pen. The number of sessions and their intervals can vary but typically consists of 3 sessions at 1-month intervals.